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PubMed COVID-19 Clinical Care

19431 - 19440 of 57354 results found

Emergence of SARS-CoV-2 variant of interest B.1.525 (Eta) in Bangladesh

Date
Saturday, October 07, 2023 - 4:00 AM
Description
In the present study, we report the complete genome of five Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) from Bangladesh harboring mutations at Spike protein (E484K, Q677H, D614G, A67V, Q52R, Y144del, H69del, V70del, F888L) assigned

Monoclonal antibodies lock down SARS-CoV-2 spike

Date
Saturday, October 07, 2023 - 4:00 AM
Description
SARS-CoV-2 rapidly accumulated mutations in its immunodominant receptor-binding domain (RBD), rendering all clinically authorized monoclonal antibodies (mAbs) ineffective. Liu et al. unveil potent human mAbs that neutralize all tested SARS-CoV-2

Induction of antiviral gene expression by cyclosporine a, but not inhibition of cyclophilin a or B, contributes to its restriction of human coronavirus 229E infection in a lung epithelial cell line

Date
Saturday, October 07, 2023 - 4:00 AM
Description
The development of antivirals with an extended spectrum of activity is an attractive possibility to protect against future emerging coronaviruses (CoVs). Cyclosporine A (CsA), a clinically approved immunosuppressive drug, has established antiviral