PubMed COVID-19 Clinical Care
23961 - 23970 of 57354 results found
Reversing the Stigma around Canada's Poor-Performing Healthcare Systems
Description
Recent statistics report that healthcare spending growth is persistently high; in recent years, spending growth exceeded 5% (CIHI 2022). Some portion of the outsized growth can be attributed to the COVID-19 pandemic, though the cause is irrelevant
A prospective study of extraesophageal reflux and potential microaspiration in patients hospitalized with COVID-19 in Jordan
Description
CONCLUSION: The study showed a high prevalence of EOR among the study cohort and provide the first prospective evidence suggesting the potential for aerodigestive pathophysiology including microaspiration in COVID-19 disease. We believe that the
The kinetics of inhibitory immune checkpoints during and post-COVID-19: the knowns and unknowns
Description
The immune system is tightly regulated to prevent immune reactions to self-antigens and to avoid excessive immune responses during and after challenges from non-self-antigens. Inhibitory immune checkpoints (IICPs), as the major regulators of immune
PNA-Pdx: Versatile Peptide Nucleic Acid-Based Detection of Nucleic Acids and SNPs
Description
Monitoring diseases caused by pathogens or by mutations in DNA sequences requires accurate, rapid, and sensitive tools to detect specific nucleic acid sequences. Here, we describe a new peptide nucleic acid (PNA)-based nucleic acid detection toolkit
Understanding Sociodemographic Factors and Reasons Associated with COVID-19 Vaccination Hesitance among Adults in Tanzania: A Mixed-Method Approach
Description
Although studies on COVID-19 vaccine hesitancy are being undertaken widely worldwide, there is limited evidence in Tanzania. This study aims to assess the sociodemographic factors associated with COVID-19 vaccine hesitancy and the reasons given by
Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir
Description
Nirmatrelvir is a specific antiviral targeting the main protease (M^(pro)) of SARS-CoV-2, and has been approved to treat COVID-19^(1,2). As an RNA virus characterized by high mutation rates, whether SARS-CoV-2 will develop resistance to nirmatrelvir
Role of histopathology in severity assessments of post-COVID-19 rhino-orbital cerebral mucormycosis - A case-control study
Description
CONCLUSION: The present study analyses the predictive role of histopathology in invasive mucormycosis. Higher fungal load, degree of angioinvasion, and the absence of granulomas are associated with advanced disease in sinonasal mucormycosis. The
A New Experience in the Turkish Health System in Response to COVID-19
Description
CONCLUSION: The results provide policy-makers with an appropriate conceptual framework to deal with the pandemic crisis that may be encountered in the future.
Community Use of Repurposed Drugs Before and During COVID-19 Pandemic in the Netherlands: An Interrupted Time-Series Analysis
Description
CONCLUSION: Dispensing of most drugs was not significantly associated with pandemic and government's response. Despite some statistically significant disruptions, these were not necessarily clinically relevant due to small absolute differences
