PubMed COVID-19 Clinical Care
23501 - 23510 of 57354 results found
Corrigendum to "Computational design of nanomolar-binding antibodies specific to multiple SARS-CoV-2 variants by engineering a specificity switch of antibody 80R using RosettaAntibodyDesign (RAbD) results in potential generalizable therapeutic antibodi...
Description
[This corrects the article DOI: 10.1016/j.heliyon.2023.e15032.].
Adrenal function in relation to cytokines and outcome in non-critically ill patients with COVID-19
Description
CONCLUSION: Our findings indicate that cortisol serves as an indicator of disease severity. GILZ expression appears to be a more effective marker of mortality prediction in moderate COVID-19 cases. However, routine measurement of GILZ levels is
Susceptibility of SARS-CoV2 infection in children
Description
Coronavirus disease 2019 in children presents with distinct phenotype in comparison to adults. Overall, the pediatric infection with a generally milder clinical course of the acute infection compared to adults still faces several unknown aspects
Investigation of circulating infectious agents in experimental Beagle dogs of a production colony and three research facilities in China from June 2021 to May 2022
Description
To understand the epizootiologic characteristics of pathogens and opportunistic infections in one Beagle dog production colony and three research facilities, viruses and mycoplasma were detected in 1777 samples collected from Beagle dogs in China by
Glucocorticoids, COVID-19 and cryptococcosis
Description
Cryptococcus neoformans and C. gattii pneumonitis could persist asymptomatically for indefinite periods, resolve, or progress to symptomatic dissemination, mainly in immunocompromised individuals (e.g., treated with corticosteroids). The symptoms of
Corrigendum to "Computational design of nanomolar-binding antibodies specific to multiple SARS-CoV-2 variants by engineering a specificity switch of antibody 80R using RosettaAntibodyDesign (RAbD) results in potential generalizable therapeutic antibodi...
Description
[This corrects the article DOI: 10.1016/j.heliyon.2023.e15032.].
Pharma - manufacturing: the unappreciated and overlooked indispensable skill
Description
The process of vaccine production, manufacturing, is time-intensive, complex, expensive, and highly technical, requiring close coordination and collaboration among multiple companies with different inputs, from active pharmaceutical ingredients to
Domain-based mRNA vaccines encoding spike protein N-terminal and receptor binding domains confer protection against SARS-CoV-2
Description
With the success of messenger RNA (mRNA) vaccines against coronavirus disease 2019, strategies can now focus on improving vaccine potency, breadth, and stability. We designed and evaluated domain-based mRNA vaccines encoding the wild-type spike
Rush hour-and-a-half: Traffic is spreading out post-lockdown
Description
Traffic congestion is ubiquitous in major cities around the world. Congestion is associated with a slew of negative effects, including delays and local air pollution. Because of the negative effects of congestion, governments invest billions of
