PubMed COVID-19 Clinical Care

Quality assessment and characterization of unregulated antiviral drugs for feline infectious peritonitis: implications for treatment, safety, and efficacy

Thursday, January 25, 2024 - 4:00 AM

OBJECTIVE: Feline infectious peritonitis is fatal, and due to lack of approved treatments, unregulated antiviral drugs are used to treat this disease. This study set out to determine the purity of various batches of these drugs from several companies

Qualitative Exploration of the Experiences of People Who Use Captagon and Therapists in Jordan

Wednesday, January 24, 2024 - 4:00 AM

Background: Captagon (Fenethylline) is an amphetamine type stimulant (ATS) and one of the most popular substances of use in the Middle East. This study aims to describe and analyze the trajectory of captagon use, severity of addiction and withdrawal

Quality of hospital care and clinical outcomes: a comparison between the Lombardy Region and the Italian national data

Wednesday, January 24, 2024 - 4:00 AM

CONCLUSIONS: The study shows the continuing decline in volumes compared to 2019 (pre-COVID), the excellent performance of hospitals in Lombardy and a relevant contribution for the volumes and the quality of outcomes of private accredited hospitals.

Quantification of hs-Troponin Levels and Global Longitudinal Strain among Critical COVID-19 Patients with Myocardial Involvement

Tuesday, January 23, 2024 - 4:00 AM

Background. Myocardial involvement among critically ill patients with coronavirus disease 2019 (COVID-19) often has worse outcomes. An imbalance in the oxygen supply causes the excessive release of pro-inflammatory cytokines, which results in

Quantitative Synthesis of Factors Associated with COVID-19 Vaccine Acceptance and Vaccine Hesitancy in 185 Countries

Monday, January 22, 2024 - 4:00 AM

Mass vaccination against COVID-19 is the best method to ensure herd immunity in order to curb the effect of the pandemic on the global economy. It is therefore important to assess the determinants of COVID-19 vaccine acceptance and hesitancy on a

Quality assessment of LNP-RNA therapeutics with orthogonal analytical techniques

Monday, January 22, 2024 - 4:00 AM

The availability of analytical methods for the characterization of lipid nanoparticles (LNPs) for in-vivo intracellular delivery of nucleic acids is critical for the fast development of innovative RNA therapies. In this study, analytical protocols to

Quality of life and healthcare utilization during the COVID-19 pandemic are more restricted in chronically ill than in healthy children: a tertiary care children's hospital experience

Monday, January 22, 2024 - 4:00 AM

The global COVID-19 pandemic forced changes in everyday life of children and adolescents due to government containment measures, an altered healthcare accessibility and utilization, and public concern about SARS-CoV-2 transmission. Data on the

Qualitative interview study of strategies to support healthcare personnel mental health through an occupational health lens

Friday, January 12, 2024 - 4:00 AM

CONCLUSIONS: Occupational health can enact strategies to support personnel mental health: to structurally sustain attention, use social cognition tools (eg, suicidality protocols or expanded job descriptions); to leverage distributed attention

Quality of life and family management of paediatric chronic condition amidst the COVID-19 pandemic

Friday, January 12, 2024 - 4:00 AM

CONCLUSIONS: Parents of children/adolescents with chronic conditions reported an average quality of life, and the COVID-19 pandemic significantly impacted the family management of chronic conditions.

Quantification of biases in predictions of protein-protein binding affinity changes upon mutations

Wednesday, January 10, 2024 - 4:00 AM

Understanding the impact of mutations on protein-protein binding affinity is a key objective for a wide range of biotechnological applications and for shedding light on disease-causing mutations, which are often located at protein-protein interfaces