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PubMed COVID-19 Clinical Care

3771 - 3780 of 4815 results found

Effect of Post-COVID-19 on Brain Volume and Glucose Metabolism: Influence of Time Since Infection and Fatigue Status

Date
Tuesday, May 16, 2023 - 4:00 AM
Description
Post-COVID-19 syndrome (PCS) fatigue is typically most severe <6 months post-infection. Combining magnetic resonance imaging (MRI) and positron emission tomography (PET) imaging with the glucose analog [^(18)F]-Fluorodeoxyglucose (FDG) provides a comprehensive overview of the effects of PCS on regional brain volumes and metabolism, respectively. The primary purpose of this exploratory study was to investigate differences in MRI/PET outcomes between people < 6 months (N = 18, 11 female) and > 6...

Evaluation of off-label rapamycin use to promote healthspan in 333 adults

Date
Tuesday, May 16, 2023 - 4:00 AM
Description
Rapamycin (sirolimus) is an FDA-approved drug with immune-modulating and growth-inhibitory properties. Preclinical studies have shown that rapamycin extends lifespan and healthspan metrics in yeast, invertebrates, and rodents. Several physicians are

Emerging patterns of substance abuse and related treatment in China

Date
Tuesday, May 16, 2023 - 4:00 AM
Description
PURPOSE OF REVIEW: The situation of China drug use has seen dramatic changes in recent years. The aim of this review is to give a perspective of the current situation of drug abuse, the problems associated with it, and the strategy to control it in

Emerging SARS-CoV-2 variants: Why, how, and what's next?

Date
Tuesday, May 16, 2023 - 4:00 AM
Description
The emergence of the SARS-CoV-2 Omicron variant poses a striking threat to human society. More than 30 mutations in the Spike protein of the Omicron variant severely compromised the protective immunity elicited by either vaccination or prior