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PubMed COVID-19 Clinical Care

1331 - 1340 of 2610 results found

Design of VA CoronavirUs Research and Efficacy Studies-1 (VA CURES-1): A double-blind, randomized placebo-controlled trial of COVID-19 convalescent plasma in hospitalized patients with early respiratory compromise

Date
Thursday, August 10, 2023 - 4:00 AM
Description
CONCLUSIONS: VA CURES-1 was a large multi-site trial designed to provide conclusive information about the efficacy of CCP in well-characterized patients at risk for progression of COVID-19. It utilized a rigorous study design with relevant initial

Diketo acid inhibitors of nsp13 of SARS-CoV-2 block viral replication

Date
Thursday, August 10, 2023 - 4:00 AM
Description
For RNA viruses, RNA helicases have long been recognized to play critical roles during virus replication cycles, facilitating proper folding and replication of viral RNAs, therefore representing an ideal target for drug discovery. SARS-CoV-2 helicase